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Neural Crest Migration Orchestrated by Molecular and Mechanical Signals

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Neural crest cells migrate over large distances in embryos, coordinating formation as subpopulations.
Established concepts include neural crest chemosensing alongside novel views on biomechanical guidance.
Proposed interactions between chemical and mechanical cues aid self-generation of guidance gradients.
Collective swarming and directional migration in an embryo's complex environment are facilitated by these mechanisms.

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Review highlights neural crest migration mechanisms in embryos, emphasizing molecular and mechanical signals.

Weißenbruch et al. (2025) studied this question.

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