Are Opioids Necessary to Control Pain after Lower Third Molar Extraction? A Triple Blind Randomized Clinical Trial

Introduction: to compare two postoperative prescriptions for pain control after extraction of lower impacted third molars (ibuprofen/acetaminophen, ibuprofen/ oxycodone). Methods: In this triple-blind, randomized, split-mouth clinical trial, 18 patients were evaluated using the following parameters: trismus, pain, alveolitis, and adverse effects (nausea, difficulty breathing, dizziness and constipation). Trismus was assessed on the seventh day after surgery, by measuring the maximum mouth opening in millimeters. The assessment of pain and adverse effects was carried out using a visual and...