Depression in orthognathic patients: clinical and genetic risk factors

Q: What type of study is this?

This is a Cross-Sectional Study study.

Delson da Costa; Rafaela Scariot; Aline Monise Sebastiani; Grasielli Vicentini; Danielle Veiga Bonotto; Michelle Nascimento Meger; Lidiana dos Santos Cordeiro

doi:10.14436/2358-2782.11.3:e252540.oar

October 1, 2025Journal of the Brazilian College of Oral and Maxillofacial Surgery

Depression in orthognathic patients: clinical and genetic risk factors

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Implication

Cross-sectional study evaluated depression prevalence and related clinical and genetic factors in malocclusion patients, highlighting the role of specific polymorphisms.

Abstract

Introduction: This study aimed to evaluate the depression prevalence in patients requiring orthognathic surgery and clinical, and genetic factors associated with depression. Methods: A cross-sectional study was performed in 143 Class II and III skeletal malocclusion patients requiring orthognathic surgery. Depression, chronic pain, somatization, and temporomandibular disorders (TMD) were assessed using the RDC/TMD. DNA was obtained from buccal cells and polymorphisms in the Dopamine Receptor D2 -DRD2- (rs6275 and rs6276) and Ankyrin Repeat and Kinase Domain Containing 1 -ANKK1- (rs1800497)...

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Cite This Study

Costa et al. (2025) studied this question.

synapsesocial.com/papers/68de5da783cbc991d0a20a7f https://doi.org/10.14436/2358-2782.11.3:e252540.oar

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Depression in orthognathic patients: clinical and genetic risk factors

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Implication

Abstract

Discussion

Cite This Study

Depression in orthognathic patients: clinical and genetic risk factors

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Implication

Abstract

Discussion

Cite This Study

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