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Digestive Neurobiology in Autism: From Enteric and Central Nervous System Interactions to Shared Genetic Pathways

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Observational analysis identifies gastrointestinal issues and genetic mutations in autism, suggesting interlinked pathways.

Gastrointestinal symptoms are prevalent in autism spectrum disorders, complicating diagnosis and management.
Research highlights significant genetic mutations affecting the enteric nervous system and gastrointestinal health.
There is reported crosstalk between the gut microbiota and both the central and enteric nervous systems.
Understanding these interactions may help in developing targeted therapies for gastrointestinal issues in autism.

Robas et al. (2025) studied this question.

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