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Ewing sarcoma: diagnosis, combination therapy. Literature review

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Literature review explores chemotherapy and molecular targeting drugs for ewing sarcoma, highlighting the challenges in treatment outcomes.

Chemotherapy has significantly improved patient outcomes for ewing sarcoma, despite treatment challenges.
High-dose chemotherapy with autologous transplantation showed contradictory effectiveness in treating advanced ewing sarcoma.
Multidrug chemotherapy regimens from the 1960s and 70s are still in use today for initial treatment in ewing sarcoma cases.
Ongoing studies explore new therapies like cytostatics combined with molecular inhibitors to advance treatment for ewing sarcoma.

Фалалеева et al. (2025) studied this question.

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Literature review explores chemotherapy and molecular targeting drugs for ewing sarcoma, highlighting the challenges in treatment outcomes.