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January 1, 2025RSC AdvancesOpen Access

Disulfiram as an anti-inflammatory agent: mechanisms, nano-delivery strategies, and applications in non-oncologic diseases

Qiwen Jiang Mengni Jiang Yanwei Lv Xinyuan Zhang Shige Wang Jiulong Zhao

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Key Points

Disulfiram exhibits significant anti-inflammatory effects, potentially aiding in various diseases.
The review identifies multiple delivery strategies for disulfiram, enhancing its therapeutic potential.
Applications of disulfiram in managing non-oncologic inflammatory diseases are explored extensively.
Understanding the mechanisms of disulfiram can lead to improved treatment methods in inflammatory conditions.

Implication

This review highlights disulfiram's anti-inflammatory mechanisms and delivery strategies for non-oncologic diseases.

Abstract

This study reviews the anti-inflammatory mechanisms of disulfiram, delivery strategies, and its applications in non-oncologic inflammatory diseases.

Discussion

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Cite This Study

Jiang et al. (2025) studied this question.

synapsesocial.com/papers/68de68ea83cbc991d0a21265 https://doi.org/10.1039/d5ra04662a

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Correction: Disulfiram as an anti-inflammatory agent: mechanisms, nano-delivery strategies, and applications in non-oncologic diseasesOriginal Research · 2026
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4Exploring the therapeutic potential of disulfiram in endometriosis: mechanisms targeting inflammation, oxidative stress, pyroptosis, and angiogenesisReview · 2026 · 2 citations
5Abstract 5738: Repurposing disulfiram for cancer: A drug delivery and population-based approach2024

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