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October 2, 2025npj Antimicrobials and ResistanceOpen Access

The butterfly effect: collateral damage and impacts of antimicrobial strategies on the oral microbiome

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Authors

JBJason L. BrownWJWilliam JohnstonMBMark C. Butcher

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Overview

This study reveals collateral damage of antimicrobial strategies on oral biofilms, suggesting potential risks for health.

Key Points

  • Unintended effects of antimicrobial use can lead to increased antimicrobial resistance in oral microbes, disrupting health.
  • Biofilm control measures can cause persistent resistant microbes to adapt, reshaping oral and systemic niches significantly.
  • Fluctuations in microbial populations are influenced by diet, hygiene, antimicrobials, and disease, affecting overall health.
  • The study highlights how microbial disruption in the oral cavity may have broader implications for human health.

Cite This Study

Brown et al. (2025) studied this question.

synapsesocial.com/papers/68de68ea83cbc991d0a2165fhttps://doi.org/10.1038/s44259-025-00156-6
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