Supplementary Data1 from ctDNA as a Molecular Biomarker in the Phase II Trial of Imatinib plus Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumor

Ciara M. Kelly; Martina Bradić; Sara Saunds; Viswatej Avutu; Lauren B. Banks; Jason E. Chan; Sandra P. D’Angelo; Mark A. Dickson; Mrinal M. Gounder; Mary Louise Keohan; Robert G. Maki; Sujana Movva; Evan Rosenbaum; Edmund K. Bartlett; Aimeé M. Crago; Brian R. Untch; Vivian E. Strong; Samuel Singer; Sinchun Hwang; Cristina R. Antonescu; Karthigayini Sivaprakasam; Maria Lapshina; Maysun Hasan; Ronak Shah; Michael F. Berger; Li‐Xuan Qin; William D. Tap; Ping Chi

doi:10.1158/1078-0432.30255701

Key Points

ctDNA levels are evaluated as a potential biomarker for treatment response.
The trial involves patients with advanced gastrointestinal stromal tumor (GIST) to determine treatment efficacy.
Conclusions highlight the relevance of ctDNA in monitoring disease progression during treatment.
Further studies are suggested to validate ctDNA's role in personalized medicine approaches.

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Implication

Phase II trial assesses ctDNA as a molecular biomarker in patients with gastrointestinal stromal tumor, indicating potential for personalized treatment.

Abstract

Representativeness of Study Participants

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Cite This Study

Kelly et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a2195b https://doi.org/10.1158/1078-0432.30255701

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Supplementary Data1 from ctDNA as a Molecular Biomarker in the Phase II Trial of Imatinib plus Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumor

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Supplementary Data1 from ctDNA as a Molecular Biomarker in the Phase II Trial of Imatinib plus Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumor

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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