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October 1, 2025Open Access

Figure S1 from A Novel Conditionally Replicative Oncolytic Adenovirus under the Control of the SALL4 Promoter Inhibits the Growth of Rhabdoid Tumors

Satoru Oya Hideki Yoshida Akimasa Tomida Mitsuru Miyachi Shigeki Yagyu Yoshiki Katsumi Ken Kikuchi Kunihiko Tsuchiya Eiichi Konishi Subbaya Subramanian Masato Yamamoto Tomoko Iehara

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Key Points

The oncolytic adenovirus significantly inhibits growth in rhabdoid tumors.
Analysis showed effective mapping of the SALL4 promoter region.
The research involved constructing a specialized oncolytic adenovirus targeting SALL4.
These findings suggest a new approach in targeting aggressive tumors using gene therapy.

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Implication

A novel oncolytic adenovirus inhibits tumor growth in rhabdoid tumors, suggesting SALL4 as a potential target.

Abstract

Figure S1 shows Map of the SALL4 promoter (pSALL4) region in human and structure of pSALL4-OAd.

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Cite This Study

Oya et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21981 https://doi.org/10.1158/1535-7163.30255533

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