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August 4, 2025

Figure S8 from m⁶A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb

Tingting Xia Menglei Chen Meiyu Zhou Weiping Wan Yifan Shan Weijia Xie Na Wu Chengying Li Zhiquan Yuan Tongjian Cai Zubin Yu Ying Xiang Li Bai Yafei Li

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Key Points

MAIN FINDING: m6A-modified SFTA1P functions as a tumor suppressor in non-small cell lung cancer.
KEY EVIDENCE: The study evaluates tumor volume changes in AAV-SFTA1P and AAV-NC treatment groups.
APPROACH: Analysis utilizes AAV vectors to deliver SFTA1P in a non-small cell lung cancer model.
SIGNIFICANCE: Findings suggest SFTA1P could be a novel target for lung cancer therapies.

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Implication

The research demonstrates that a tumor suppressor regulates tumor volume in non-small cell lung cancer, suggesting new therapeutic targets.

Abstract

Tumor volume of AAV-SFTA1P and AAV-NC treatment group

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Cite This Study

Xia et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0982 https://doi.org/10.1158/1541-7786.29819529

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S2 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
2Figure S4 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
3Figure S1 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
4Figure S3 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
5Figure S6 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025

Figure S5 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
Table S1 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
Figure S7 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025