Figure S7 from m⁶A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb

Tingting Xia; Menglei Chen; Meiyu Zhou; Weiping Wan; Yifan Shan; Weijia Xie; Na Wu; Chengying Li; Zhiquan Yuan; Tongjian Cai; Zubin Yu; Ying Xiang; Li Bai; Yafei Li

doi:10.1158/1541-7786.29819532

August 4, 2025

Figure S7 from m⁶A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb

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Key Points

MAIN FINDING: The m6A-modified SFTA1P acts as a tumor suppressor in non-small cell lung cancer.
KEY EVIDENCE: YTHDC1 expression differences in A549 and H1299 cells were analyzed using qRT-PCR and western blotting.
APPROACH: The study involved genetically modified cell lines and examined the regulation of TGFBR2 and P-TEFb.
SIGNIFICANCE: Understanding the tumor suppressor role may help develop targeted therapies for non-small cell lung cancer.

Implication

Experimental analysis shows that YTHDC1 affects tumor suppressor activity in non-small cell lung cancer, indicating its role in regulating critical pathways.

Abstract

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Cite This Study

Xia et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d097f https://doi.org/10.1158/1541-7786.29819532

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Figure S7 from m⁶A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb

Key Points

Implication

Abstract

Discussion

Cite This Study

Figure S7 from m⁶A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb

Key Points

Implication

Abstract

Discussion

Cite This Study

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