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August 4, 2025

Figure S6 from m⁶A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb

Tingting Xia Menglei Chen Meiyu Zhou Weiping Wan Yifan Shan Weijia Xie Na Wu Chengying Li Zhiquan Yuan Tongjian Cai Zubin Yu Ying Xiang Li Bai Yafei Li

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Key Points

SFTA1P is identified as a tumor suppressor in non-small cell lung cancer through m6A modification.
The study demonstrates that SFTA1P regulates TGFBR2 and P-TEFb, important in cancer pathways.
SRAMP prediction server was used to identify m6A modification sites in the SFTA1P sequence.
Understanding SFTA1P's role may enhance therapeutic strategies for treating non-small cell lung cancer.

Implication

Research reveals SFTA1P's role in regulating TGFBR2 and P-TEFb in non-small cell lung cancer, indicating pathway involvement.

Abstract

The m6A RNA modification sites in SFTA1P sequence identified by using SRAMP prediction server (http://www.cuilab.cn/sramp)

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Cite This Study

Xia et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d098e https://doi.org/10.1158/1541-7786.29819535

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S4 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
2Figure S1 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
3Figure S3 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
4Figure S2 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
5Table S1 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025

Figure S5 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
Figure S8 from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025
Data from m<sup>6</sup>A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb2025