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Observational analysis shows 71% reduction in tumor size for neurofibromatosis type 1 patients, indicating cryoablation's safety and effectiveness.
Percutaneous cryoablation is a promising minimally invasive treatment for unresectable plexiform neurofibromas (PNs) in adults with neurofibromatosis type 1 (NF1). In this study, cryoablation reduced tumor size by at least 20% in 71% of treated cases, with most patients reporting improved pain and quality of life. The procedure was well-tolerated with no severe complications, highlighting its potential as a safe alternative to surgery.
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Belkaïd et al. (2025) studied this question.
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