Observational analysis reveals best overall response in advanced breast cancer patients, suggesting potential benefits of novel combination therapy.
Best overall response and target lesion improvement. Percentage change from baseline in the sum of the diameters of all target lesions at the time of best response. There were five subjects with 100% target lesion responses, but they were classified as PR due to nontarget lesions. Each bar represents a single patient with no prior systemic therapy for advanced breast cancer in the response evaluable set (N = 33).
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Wesolowski et al. (2025) studied this question.
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