Supplementary Figure S11 from Integrated Omics and Multicohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer

Key Points

The identified enhancer variant is linked to ferroptosis, potentially improving treatment strategies.
A novel ferroptosis-related gene signature was constructed, indicating its relevance in prostate cancer.
Multicohort analyses provided robust validation for the gene signature, enhancing its clinical applicability.
Findings may enable more targeted precision therapy options for patients with prostate cancer.

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Multicohort analyses reveal an enhancer variant linked to ferroptosis, suggesting new precision therapy approaches for prostate cancer.

Construction and validation of ferroptosis-related gene signature

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Ma et al. (2025) studied this question.

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