Supplementary Figure S12 from Integrated Omics and Multicohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer

Key Points

The ferroptosis-related gene signature predicts prognosis in prostate cancer patients, improving therapeutic strategies.
Time-dependent ROC curves illustrate the signature's performance, offering a promising tool for patient stratification.
Multicohort analyses reinforce the reliability of results, supporting broader application within clinical frameworks.
Enhanced understanding of enhancer variants may inform targeted treatments, potentially transforming management of prostate cancer.

Analysis demonstrates the prognostic significance of a ferroptosis-related gene signature, suggesting precision therapy implications.

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Ma et al. (2025) studied this question.

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