Supplementary Figure S5 from Integrated Omics and Multicohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer

Key Points

An enhancer variant was identified linking ferroptosis to responses in precision therapy for prostate cancer, enhancing treatment options.
NCOA4 is associated with prostate cancer progression, suggesting it may be a vital target in precision treatment strategies.
Integrated omics and multicohort analyses revealed significant relationships between ferroptosis and therapeutic outcomes.
The findings underscore the potential for using genomic insights to tailor treatments according to individual cancer profiles.

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Integrated omics and multicohort analyses show a link between ferroptosis and therapy response in prostate cancer, indicating NCOA4's role.

NCOA4 is related to the progression of prostate cancer.

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Ma et al. (2025) studied this question.

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