Case-control study highlights IL-8's role in diagnosing bacterial pneumonia, suggesting accurate identification of patients.
Key Points
Mean serum il-8 levels were significantly higher in pneumonia patients (92.4 pg/ml) compared to controls (35.7 pg/ml), indicating strong potential for diagnosis.
At a cut-off value of 60.0 pg/ml, il-8 demonstrated a sensitivity of 87.8% and specificity of 81.5%, supporting its use as a diagnostic biomarker.
ROC curve analysis showed strong diagnostic accuracy of il-8 with an area under the curve of 0.902, underscoring its reliability in clinical settings.
Patients infected with Klebsiella pneumoniae and Pseudomonas aeruginosa exhibited the highest serum il-8 concentrations, suggesting variability based on bacterial etiology.