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This is a Systematic Review study.

October 2, 2025MedicinaOpen Access

Hydatidiform Mole with Coexisting Normal Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis

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Neonatal mortality is predominantly linked to prematurity, particularly for infants delivered before 32 weeks.
Among 118 pregnancies with hydatidiform mole coexisting with a live fetus, most were complete moles at a median delivery of 31.6 weeks.
Cesarean delivery was performed in 79% of cases, often due to mole-related factors, with no significant improvement in maternal or oncologic risk.
Severe preeclampsia correlated with earlier deliveries, leading to potential complications and adverse outcomes.

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Systematic review evaluates outcomes of hydatidiform mole with live fetus pregnancies, suggesting cesarean delivery does not reduce risks.

Zorzato et al. (2025) studied this question.

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Systematic review evaluates outcomes of hydatidiform mole with live fetus pregnancies, suggesting cesarean delivery does not reduce risks.