INVESTIGATION OF LIPOPHILIC COMPONENTS OF RHEUM TATARICUM L.f.

Despite the widespread use of Rheum tataricum L.f. (genus Rheum L., family Polygonaceae Juss.) in phytotherapy, its lipophilic components remain insufficiently studied. In this study, we analyzed the lipophilic composition of hexane extracts obtained from Rheum tataricum L.f. Plant material was harvested during the fruiting phase in the Almaty region. Metabolites were determined by gas chromatography-mass spectrometry (GC-MS). The Agilent MSD ChemStation software (version 1701EA) was used to control the gas chromatography system, record and process the obtained results and data. As a result of the study, 11 lipophilic components were found in the underground part, of which 7 were identified; in the aboveground part – 23 components, 12 compounds were identified. The main metabolites of the hexane extract obtained from the underground part of the plant are β-sitosterol (63.23%), campesterol (11.94%) and octacosanol (8.45%). Steroid components predominate among the identified compounds. In the aboveground part, β-sitosterol (28.92%), squalene (16.22%), γ-tocopherol (11.73%) and α-amyrin (4.64%) are dominant. The total proportion of identified components contained in the hexane extracts for the underground part was 91.20%, and for the aboveground part – 76.29%, respectively. Terpenoid compounds predominate in the studied extracts, which indicates potential biological activity and value for conducting further research.