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October 2, 2025Lara D. VeekenOpen Access

Predicting rapid radiographic progression in difficult-to-treat rheumatoid arthritis: insights from long-term follow-up

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Rapid radiographic progression was observed in 50% of poly-refractory RA patients, indicating a need for targeted interventions.
Mean annual mSvdH progression was notably higher for persistent inflammatory refractory RA patients at 3.3 units compared to 2.4 units in others.
Longitudinal assessment showed older age and swollen joint count to be significant predictors of rapid radiographic progression.
Findings suggest many difficult-to-treat RA cases are at least partially controlled, showcasing the need for individualized treatment strategies.

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Observational analysis highlights predictors of rapid radiographic progression in rheumatoid arthritis, indicating treatment variability.

Abacar et al. (2025) studied this question.

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