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October 2, 2025Pediatrics in Review

Fever, Joint Pain, and Weight Loss in a 19-Year-Old Male Adolescent

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Authors

DGDanoucheka GelinChildren's National MRMargarita RamosChildren's National EFEmma FrostChildren's National

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Implication

Case report highlights elevated inflammatory markers and multiple symptoms in a patient with fever and joint pain, suggesting adult-onset still disease.

Key Points

Adult-onset still disease was diagnosed after excluding infections and other rheumatologic conditions.
The patient presented with arthralgia, intermittent fever, and elevated inflammatory markers such as C-reactive protein and ferritin.
Effective management included interleukin-1 inhibitors after glucocorticoids failed to improve symptoms significantly.
Regular follow-up indicated that symptoms remain under control without relapses for over 15 months.

Cite This Study

Gelin et al. (2025) studied this question.

synapsesocial.com/papers/68de8eaeaa6cec72c69ea921 https://doi.org/10.1542/pir.2023-006004

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Implication

Case report highlights elevated inflammatory markers and multiple symptoms in a patient with fever and joint pain, suggesting adult-onset still disease.

Fever, Joint Pain, and Weight Loss in a 19-Year-Old Male Adolescent

Discussion

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Implication

Key Points

Cite This Study

Fever, Joint Pain, and Weight Loss in a 19-Year-Old Male Adolescent

Discussion

Member takes

Implication

Key Points

Cite This Study

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