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October 3, 2025BMC MicrobiologyOpen Access

Investigation of prevalence and phylogenetic classification of Microsporidia MB and insecticide target site insensitivity resistance mutations in Anopheles gambiae s.l. and Anopheles funestus mosquitoes from Busia, Kenya

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Authors

HWHerzel Tiffany WanderaGNGodfrey NattohDKDaniel Kiboi

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Overview

Study examines microsporidia mb prevalence and insecticide resistance in Anopheles species, highlighting challenges for malaria control.

Key Points

  • Microsporidia mb prevalence in An. gambiae s.l. was low to moderate, with significant variation across sub-counties.
  • An. gambiae s.l. showed a 5.94 higher odds of microsporidia mb infection compared to An. arabiensis.
  • Insecticide resistance genotyping revealed high frequencies of kdr-East (94.7%) and kdr-West (60%) mutations.
  • Phylogenetic analysis placed microsporidia mb from Busia closely related to original Ahero reference, indicating shared ancestry.

Cite This Study

Wandera et al. (2025) studied this question.

synapsesocial.com/papers/68e02f34f0e39f13e7fa20c2https://doi.org/10.1186/s12866-025-04324-6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Different agroecosystems have similar Anopheles–Microsporidia MB infection dynamics in the Ahero region of Western Kenya: implications for symbiont control strategies2026
  2. 2Insecticide resistance profiles of Anopheles arabiensis and relationship with Microsporidia MB infection in two rice agroecosystems in Kenya2026 · 2 citations
  3. 3Molecular detection and maternal transmission of Microsporidia MB in the field-caught Anopheles coluzzii in Cameroon2026
  4. 4Seasonal variability in the distribution of <i>Microsporidia</i> <i>MB</i> infection in <i>Anopheles gambiae</i> in a rice-growing area of Benin2025
  5. 5The L1014F Kdr mutation is associated with a higher prevalence and load of the Plasmodium-blocking symbiont Microsporidia MB In Anopheles Gambiae s.l. In Benin2026