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This is a Experimental Study study.

Alkenyl- and Aryl-Borane Nucleophiles in Enantioselective Iridium-Catalyzed Allylic Substitution of Vinyl Epoxides

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This research demonstrates enantioselective allylic substitution in vinyl epoxides, highlighting mechanistic insights into boronate interactions.

The study demonstrates effective enantioselective allylic substitution for accessing chiral amines through Ir-catalysis.
High stereoselectivity is achieved via tandem dynamic kinetic resolution and kinetic resolution in a novel approach.
The methodology shows practical utility in synthesizing (R)-pyricuol, underscoring its application potential in organic synthesis.
Mechanistic studies reveal stabilizing interactions between alkenyl boronates and electrophiles are critical for transition state formation.

Wen et al. (2025) studied this question.

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This research demonstrates enantioselective allylic substitution in vinyl epoxides, highlighting mechanistic insights into boronate interactions.