Systematic review analyzes efficacy and safety of lung volume reduction therapies in COPD patients, suggesting improvements in hyperinflation outcomes.
Background Severe emphysema, a major chronic obstructive pulmonary disease (COPD) phenotype characterized by hyperinflation, is associated with significant morbidity and mortality. Lung volume reduction (LVR) therapies, including surgical (LVRS) and bronchoscopic techniques (e.g. endobronchial valves (EBVs) and coils (ECs)), aim to reduce hyperinflation and improve outcomes, but their comparative efficacy and safety are unclear.
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Bo et al. (2025) studied this question.
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