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October 3, 2025Frontiers in EndocrinologyOpen Access

Association between the triglyceride-glucose index and hyperuricemia: potential role of obesity in patients with Type 2 diabetes mellitus

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Authors

DTDou TangXGXi GuYXYan Xuan

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Overview

Cross-sectional study shows the triglyceride-glucose index links to hyperuricemia in T2DM, suggesting obesity plays a role.

Key Points

  • Each unit increase in the triglyceride-glucose index independently raised hyperuricemia risk by 36%.
  • The study observed a 30.7% prevalence of hyperuricemia among adults with type 2 diabetes.
  • Mediation analysis revealed that body mass index contributes 20.0% to the relationship with hyperuricemia.
  • Consistent associations were found across various patient subgroups, reaffirming the findings.

Cite This Study

Tang et al. (2025) studied this question.

synapsesocial.com/papers/68e02f40f0e39f13e7fa2a1dhttps://doi.org/10.3389/fendo.2025.1637543
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