This review explores bioactive glass nanoparticles synthesis through sol-gel method, highlighting applications in drug delivery and bone regeneration.
Bioactive glass nanoparticles (BGNs) are potentially significant in the biomedical field because of their bioactive, biocomposite, and versatile nature of applications in various therapeutic fields. This review discusses the synthesis of BGNs through the sol-gel method, which is a low-temperature process, offering the opportunity to achieve a controlled composition of the BGNs for their application in medicine. The morphological, structural, and chemical characterization methods are explained to show how these properties affect the bioactivity of BGN and its fitness for a particular application. BGNs have been effectively used in bone regeneration, drug delivery, antibacterial treatments, and wound healing due to their ability to combine with bone tissue, release therapeutic ions, and deliver the drug accordingly. It also points to future possibilities of BGNs in more sophisticated areas, such as cancer treatment and bioimaging, and calls for more design in strengthening their applications in healthcare-related fields. This evaluation highlights the role of BGNs in promoting the progress of biomedical science and substantiates the possibility of providing a substantial contribution to personalized and regenerative medicine.
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Al-lamei et al. (2025) studied this question.
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