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This is a Literature Review study.

October 3, 2025Open Access

Physical exercise as a modulator of the immune system

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Regular moderate-intensity exercise enhances immune defense cells and their functions through various hormonal actions.
Increased release of anti-inflammatory myokines like IL-6 and IL-10 contributes to health, while reducing harmful pro-inflammatory mediators.
High-intensity exercise may lead to immunosuppression, increasing risks of respiratory infections and cardiovascular issues.
Moderate and consistent exercise is important for maintaining immune health, particularly in the context of chronic diseases.

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Implication

Literature review highlights how moderate exercise improves immune response, impacting diseases like type 2 diabetes and outcomes from COVID-19 vaccinations.

Cite This Study

Mesquita et al. (2025) studied this question.

synapsesocial.com/papers/68e03501f0e39f13e7fa3781 https://doi.org/10.70164/ihsr.v1i4.56

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Implication

Literature review highlights how moderate exercise improves immune response, impacting diseases like type 2 diabetes and outcomes from COVID-19 vaccinations.

Physical exercise as a modulator of the immune system

Key Points

Discussion

Implication

Cite This Study

Physical exercise as a modulator of the immune system

Key Points

Discussion

Implication

Cite This Study

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