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October 3, 2025Clinical ChemistryOpen Access

B-093 Measles Seroprevalence and Immune Gaps Among Healthcare Workers, Including Occupational and Test Method Comparisons

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Authors

HCHyun-Woo ChoiChonnam National University HospitalSLS. Y. LeeJCJeong‐Hwa ChoiKonkuk University Medical Center

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Implication

Observational analysis assessed measles immunity in healthcare workers, indicating significant immune gaps and assay discrepancies.

Key Points

  • Measles seroprevalence among healthcare workers was found to be 90.9%, showing no significant difference between medical and non-medical personnel.
  • Seroprevalence was highest in individuals born before 1972 at 95.2-96.0%, declining in subsequent birth years and showing variation across age groups.
  • Analysis used ELISA and CLIA to detect IgG antibodies, revealing seropositivity rates of 46.7% and 90.7%, respectively, with only slight agreement between assays.
  • The results underscore the need for careful selection of serological assays for measles immunity assessment, as discrepancies highlight potential immune gaps.

Cite This Study

Choi et al. (2025) studied this question.

synapsesocial.com/papers/68e040e9a99c246f578b3019https://doi.org/10.1093/clinchem/hvaf086.491
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Measles Seroprevalence Among Healthcare Workers in a Tertiary Hospital in Central Greece, 20172026
  2. 2Measles serostatus among health care workers in a university clinic in Hungary in 20242026
  3. 3Assessment of immunity to the measles virus through the detection of IgG antibodies2025
  4. 4The prevalence of measles vaccination in measles-infected healthcare workers: A systematic review and meta-analysis2026
  5. 5Measles and Rubella Immunity Profile of Healthcare Workers in Bulgaria: A Cross-Sectional Study2026