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This is a Quantitative Study study.

October 3, 2025Clinical ChemistryOpen Access

B-037 Configuration and validation of urine oxalate open channel assay on the Roche Cobas c503

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The assay demonstrated excellent precision with coefficient variations of 1.68% and 0.72% for low and high quality controls.
Correlation studies showed an impressive correlation (r = 0.9998) between Roche cobas c502 and c503 analyzers using patient samples.
Linearity was verified up to concentrations of 2000 µmol/L, establishing a wide analytical measuring range for urine oxalate.
The limit of detection for the assay was determined to be 2.9 µmol/L, ensuring reliability in clinical diagnostics.

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This study evaluates the performance of urine oxalate measurements in hyperoxaluria patients, indicating the assay's reliability on Roche cobas c503.

Lu et al. (2025) studied this question.

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This study evaluates the performance of urine oxalate measurements in hyperoxaluria patients, indicating the assay's reliability on Roche cobas c503.