A-100 The evaluation of kidney injury molecule and neutrophil gelatinase associated lipocalin as predictive biomarkers of acute kidney injury in a subset of Jamaican patients undergoing cardiopulmonary bypass surgery
Prospective pilot study assesses NGAL and KIM-1 as biomarkers for AKI in patients undergoing cardiopulmonary bypass, indicating early detection importance.
Key Points
NGAL demonstrated excellent predictive ability for AKI at 2 hours post-surgery, with an AUC of 0.925.
Four patients developed AKI and prolonged cardiopulmonary bypass was a significant risk factor for these cases.
Serum creatinine levels rose early in AKI patients, with sensitivity and specificity improving significantly at 4 and 24 hours.
KIM-1 was not statistically significant for early AKI detection, highlighting the superiority of urine NGAL.