October 3, 2025Journal of Anesthesiology and Clinical ResearchOpen Access

Inappropriate Empirical Antibiotic Therapy and Mortality in Critical Illness: A Retrospective Cohort Study with Propensity Score Analysis in an Indonesian ICU

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Inappropriate empirical antibiotic therapy significantly increased 28-day mortality rates in critically ill patients.
The analysis revealed a staggering mortality rate of 77.8% among those receiving inappropriate antibiotics compared to 8.1% in those receiving appropriate therapy.
This study employed rigorous methodologies like propensity score matching and multivariate regression to draw its conclusions.
Urgent action for better antimicrobial stewardship is needed to address high inappropriateness rates seen in local prescribing patterns.

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Implication

Retrospective cohort study links inappropriate empirical antibiotic therapy to higher mortality in ICU patients, highlighting issues with antimicrobial resistance.

Cite This Study

Viandini et al. (2025) studied this question.

synapsesocial.com/papers/68e040f7a99c246f578b3afa https://doi.org/10.37275/jacr.v6i2.807

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Implication

Retrospective cohort study links inappropriate empirical antibiotic therapy to higher mortality in ICU patients, highlighting issues with antimicrobial resistance.

Inappropriate Empirical Antibiotic Therapy and Mortality in Critical Illness: A Retrospective Cohort Study with Propensity Score Analysis in an Indonesian ICU

Key Points

Discussion

Implication

Cite This Study

Inappropriate Empirical Antibiotic Therapy and Mortality in Critical Illness: A Retrospective Cohort Study with Propensity Score Analysis in an Indonesian ICU

Key Points

Discussion

Implication

Cite This Study

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