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October 3, 2025Pakistan Journal of Scientific Research

HybridSVG: Ensemble Framework for Detecting Spatially Variable Genes in Spatial Transcriptomics using Fusion of Global and Local Autocorrelation

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Authors

SHShabir HussainHMHassan MunirNBNimra Bukhari

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Overview

Ensemble framework HybridSVG detects spatially variable genes using global and local autocorrelation, highlighting its versatility in analyzing complex data.

Key Points

  • HybridSVG captures both broad tissue-wide gradients and fine-grained spatial niches with greater precision.
  • Genes identified by HybridSVG show stronger spatial autocorrelation and clearer local clustering.
  • The framework integrates global and local spatial autocorrelation measures effectively.
  • HybridSVG provides a versatile tool for analyzing spatial transcriptomics data across different species.

Cite This Study

Hussain et al. (2025) studied this question.

synapsesocial.com/papers/68e040f7a99c246f578b3ccehttps://doi.org/10.57041/pefp6a13
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