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October 5, 2025American Journal of Industrial MedicineOpen Access

Sulfur Dioxide‐ and Fluoride‐Associated Declines in Lung Function Over an 11‐Year Observation Among Aluminum Smelter Workers

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Authors

EREdite Macaringue RajaSHSujatha HariparsadRNR Naidoo

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Overview

Retrospective analysis shows significant declines in lung function among aluminum smelter workers, indicating harmful effects of sulfur dioxide and fluoride exposure.

Key Points

  • Significant decline of 2.9% in forced expiratory volume was linked to cumulative sulfur dioxide exposure.
  • Spirometric assessments indicated a 0.21% decline in FEV1/FVC ratio over ten years among continuous participants.
  • Mixed-effect models suggested a strong association between fluoride exposure and lung function decline.
  • Occupational exposure levels of both gases remained within prescribed limits despite observed lung function declines.

Cite This Study

Raja et al. (2025) studied this question.

synapsesocial.com/papers/68e22da774308421369af008https://doi.org/10.1002/ajim.70023
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exposure to Polycyclic Aromatic Hydrocarbons, but Not to Dust or Fluorides, in the Norwegian Aluminum Industry Is Associated With Accelerated Annual Decline in Lung Function2026
  2. 2Twenty‐Year Longitudinal Cohort Study of Cancer Incidence and Mortality Among Workers in Two Primary Aluminum Prebake Smelters2026
  3. 3Airborne Pollutants and Their Relation to Pulmonary Impairment and X-Ray Repair Cross-Complementing 1 Gene Variants in Aluminum Smelter Workers2026
  4. 4Mortality and cancer morbidity in workers from an aluminium smelter with prebaked carbon anodes--Part I: Exposure assessment.1995 · 23 citations
  5. 5Longitudinal and Cross-Sectional Analyses of Lung Function in Steelworkers1996 · 67 citations