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October 5, 2025INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH

Use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Opioids in the Treatment of Musculoskeletal Injuries in Athletes and Physical Activity Practitioners: Evidence and Risks Medications in Clinical Orthopedics

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Authors

DCDione Seabra de CarvalhoGGGustavo Gir GomesGYGiovana Casarini Yamashiro

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Overview

Cohort studies reveal the safety risks of NSAIDs and opioids in athletes, highlighting the need for careful use.

Key Points

  • NSAIDs effectively relieve acute pain and inflammation in injuries, but their long-term benefits remain unproven.
  • Significant risks of NSAIDs include gastrointestinal and cardiovascular issues, particularly threatening for athletes.
  • Efficacy of opioids in musculoskeletal injuries is limited to severe cases, posing substantial risks of dependence.
  • A rational, multifaceted treatment strategy prioritizing non-pharmacological therapies is essential for recovery.

Cite This Study

Carvalho et al. (2025) studied this question.

synapsesocial.com/papers/68e24e60d6d66a53c2473475https://doi.org/10.58806/ijhmr.2025.v4i8n03
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