Observational analysis shows increased mental health issues in individuals with iron deficiency anemia, highlighting significant health concerns.
Objective Iron deficiency anemia is one of the most common nutritional disorders in the world, particularly among women and children. This condition, caused by insufficient iron levels in the body, not only affects physical performance and reduces energy but can also have a significant impact on mental health. This study compared the general health and mental health of individuals with iron deficiency anemia with that of healthy individuals. Method Healthy individuals and those with iron deficiency anemia were assessed at the Aramesh Pathobiology and Genetics Laboratory in Tehran, Iran. Participants were a convenience sample of 170 healthy individuals and 170 individuals with iron deficiency anemia. Data were collected using the General Health Questionnaire and the Irritability Questionnaire. Results Individuals with iron deficiency anemia scored higher than healthy individuals on somatic symptoms, anxiety and insomnia, social dysfunction, and depression. Irritability was also significantly higher in this group, indicating a possible negative impact of iron deficiency anemia on emotional regulation. Furthermore, irritability and social dysfunction strongly predicted iron deficiency anemia. Conclusion Iron deficiency anemia increases the risk of symptoms of mental disorder, including depression, anxiety, irritability, insomnia, social dysfunction, as well as symptoms of physical health problems.
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Zamani et al. (2025) studied this question.
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