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October 5, 2025Acupuncture in Medicine

Effect of electroacupuncture on interleukin-6 and procalcitonin expression in the astrocytes and neurons of the spinal cord dorsal horn in a rat model of incisional pain

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Authors

YJYing JinLMLiqian MaQCQingfeng Cui

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Overview

Experiment reveals electroacupuncture reduces interleukin-6 and procalcitonin in rats with incisional pain, suggesting a pain relief mechanism.

Key Points

  • Electroacupuncture significantly reduces interleukin-6 and procalcitonin expression in spinal dorsal horn astrocytes and neurons.
  • Mechanical pain withdrawal threshold improved after electroacupuncture in rats with incisional pain model at 2 Hz and 20/100 Hz.
  • Use of Western blotting and enzyme-linked immunosorbent assay employed to analyze cytokine expression in spinal cord.
  • Findings indicate that electroacupuncture may serve as a therapeutic option for managing postoperative pain via cytokine modulation.

Cite This Study

Jin et al. (2025) studied this question.

synapsesocial.com/papers/68e2537cd6d66a53c247452ahttps://doi.org/10.1177/09645284251379490
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