Case report highlights successful management of an accidental intrathecal tranexamic acid injection in a 17-year-old, suggesting a need for vigilance in drug administration.
Inadvertent intrathecal tranexamic acid injection remains one of the reasons for avoidable morbidity and mortality complications in African countries. A recent review in Anaesthesia highlighted 21 such cases between 1988 and 2018, 10 of which were fatal representing mortality rate above 50%. This is the first successful case report recorded in Zambia, involving a female 17 years old scheduled for an elective exploratory laparotomy due to pelvic mass, who received TXA intrathecally in place of Bupivacaine. The article is emphasizing importance of vigilance in drug administration and early management of such complications.
No takes yet. Share an insight, caveat, or question.
Danylov et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: