Evaluation of ozonoid olive oil as an indirect pulp capping agent in permanent molars: A randomized clinical trial

Context: Preserving pulp vitality is essential for maintaining tooth integrity, making indirect pulp capping (IPC) a preferred treatment for deep carious lesions. Traditional materials such as calcium hydroxide and mineral trioxide aggregate (MTA) promote dentin repair but have limitations. Aims: To evaluate the clinical success of ozonated olive oil as an IPC agent compared to MTA and Dycal in the treatment of deep carious lesions in permanent molars. Subjects and Methods: A randomized clinical trial was conducted on 60 patients aged 19–40 years, divided into three groups receiving IPC with ozonated olive oil, MTA, or Dycal. Clinical and radiographic evaluations were performed at 3 and 6 months to assess treatment success. Results: After 6 months, MTA had the best effectiveness rate (94%), followed by ozonated olive oil (89%) and Dycal (75%). Ozonated olive oil has shown considerable microbial reduction and dentin remineralization. Conclusions: Ozonated olive oil proved to be an effective IPC agent, exhibiting strong antimicrobial properties and promoting dentin remineralization. Clinical Significance: Ozonoid olive oil can be considered a potential indirect pulp capping agent in permanent teeth due to its antimicrobial properties and ability to reduce bacterial load in dentinal caries.