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The Clinico-Radiological Effect of Vitamin D in Treatment of Osteoarthritis of the Knee: A Randomized Control Trial

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Randomized control trial shows vitamin D reduces pain and improves cartilage in knee osteoarthritis, indicating potential benefits.

Vitamin D treatment improved pain and functionality for patients with knee osteoarthritis.
At 12 months, cartilage thickness showed significant improvement in the vitamin D group compared to placebo.
Patients were monitored over a 12-month period using validated measures of pain and cartilage thickness.
The findings highlight the need for further standardization in studies exploring vitamin D's role in knee osteoarthritis treatment.

Singh et al. (2025) studied this question.

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