Medication-related osteonecrosis of the jaw (MRONJ) refers to the condition where the maxillary or mandibular bone becomes exposed and necrotic as a result of bisphosphonate therapy. The number of patients on bisphosphonates is increasing and so are the MRONJ cases. Since the initial data were published in the early 2000s, research into MRONJ has expanded significantly to enhance the understanding of this emerging condition. Various treatment options are available, but none have been established as the definitive "gold standard" for managing this disease. Hyperbaric oxygen therapy (HOT) is one of the treatment modalities for MRONJ, which has generated successful outcomes and an improvement in the quality of life along with a reduction in morbidity, as mentioned in the literature. We validate this by reporting a case of MRONJ successfully treated with HOT.
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Anand et al. (2024) studied this question.
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