Supplementary Fig. S3 from Perivascular NOTCH3⁺ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy

Supplementary Fig. 3. NOTCH3 immunohistochemistry across meningioma WHO grades. NOTCH3 expression is predominantly restricted to the perivascular niche in WHO grade 1 meningiomas in A, but extends beyond the perivascular niche in WHO grade 2 meningiomas in B and in WHO grade 3 meningiomas in C. SF numbers indicate individual meningiomas. WHO grade defined using histological criteria. Representative of n=10 meningiomas per grade. Scale bar, 100µm.