Supplementary Figures S1-S6 from Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial Calcium

Supplementary Figure 1. Comprehensive RNA-Seq and CITE-Seq analysis of venetoclax sensitive versus resistant AML specimens. Supplementary Figure 2. Further Characterization of BCL-2/SERCA3 Relationship and Role of SERCA3 in Primary Human AML Cells. Supplementary Figure 3. BCL-2 Interactors and Characterization of additional MCU Inhibitors in Venetoclax Resistant ROS-low AML cells. Supplementary Figure 4. Effects of Chemotherapeutic agents on AML Function. Supplementary Figure 5. Effects of Mitoxantrone on In Vivo PDX Experiments. Supplementary Figure 6. Effects of Extracellular Calcium Addition on Mitochondrial Calcium Content in Primary Human AML cells.