Supplementary Figure S5 from CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis

Sunil Acharya; Rafet Başar; May Daher; Hind Rafei; Ping Li; Nadima Uprety; Emily L. Ensley; Mayra Shanley; Bijender Kumar; Pinaki P. Banerjee; Luciana Melo Garcia; Paul Lin; Vakul Mohanty; Kun Hee Kim; Xianli Jiang; Yuchen Pan; Ye Li; Bin Liu; Ana Karen Nunez Cortes; Chenyu Zhang; Mohsen Fathi; Ali Rezvan; Melisa J. Montalvo; L. Sophia; Francia Reyes-Silva; Rejeena Shrestha; Xingliang Guo; Kiran Kundu; Alexander Biederstädt; Luis Muniz-Feliciano; Gary Deyter; Mecit Kaplan; Xin Ru Jiang; Enli Liu; Antrix Jain; Jason Roszik; Natalie W. Fowlkes; Luisa M. Solis Soto; Maria Gabriela Raso; Joseph D. Khoury; Pei Lin; Francisco Vega; Navin Varadarajan; Ken Chen; David Marín; Elizabeth J. Shpall; Katayoun Rezvani

doi:10.1158/2159-8290.27168669

Abstract

In a PDX mouse model of metastatic breast cancer, CAR27-28ζ NK cells lead to a reduction in tumor size and increased NK cell infiltration in the lungs.

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Acharya et al. (2024) studied this question.

synapsesocial.com/papers/68e55da7e2b3180350efade0 https://doi.org/10.1158/2159-8290.27168669

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Supplementary Figure S5 from CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis

Abstract

Discussion

Cite This Study

Supplementary Figure S5 from CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis

Abstract

Discussion

Cite This Study

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