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October 3, 2024Future Medicinal Chemistry

3,5-disubstituted pyridines with potent activity against drug-resistant Mycobacterium tuberculosis clinical isolates

Komal G. Sangu Azger Dusthackeer Vishal Singh Shivani Maykalwar Eruva Vamshi Krishna B Angayarkanni Rahul Maitra Sidharth Chopra Sunil Misra Haridas B. Rode

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Abstract

We designed and synthesized a series of compounds with a 3,5-disubstituted pyridine moiety and evaluated them against

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Cite This Study

Sangu et al. (2024) studied this question.

synapsesocial.com/papers/68e55ee1e2b3180350efb879 https://doi.org/10.1080/17568919.2024.2403963

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Novel Pyrazole-Containing Compounds Active against Mycobacterium tuberculosisOriginal Research · 2019 · 51 citations
2Exploration of Pyridine‐4‐hydrazide Derivatives as Promising Antitubercular Agents: Synthesis, Biological Evaluation, and In Silico Studies2025 · 6 citations
3Synthesis and biological evaluation of novel thioureas containing pyridine derivatives against <i>Mycobacterium tuberculosis</i>2025 · 4 citations
4Design, synthesis and antitubercular evaluation of 2,5-disubstituted 1,3,4-oxadiazoles bearing a 3,5-dinitrophenyl pharmacophoreOriginal Research · 2026
5Imidazo[1,2‐<i>a</i>]pyrimidine‐Linked Pyridine, Pyrazine, and Pyrimidine Derivatives: Design, Synthesis, and Antitubercular Activity Evaluation2025 · 3 citations

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In silico design and synthesis of novel thiazole derivatives as antitubercular agents2025
Design, Synthesis, and In-vitro anti-tuberculosis activity of 2-substituted-1,5-diphenyl-1,2-dihydro-3H-1,2,4-triazole-3-thione Derivatives2024

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