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October 2, 2024Biomedical ReportsOpen Access

Salidroside rescues hypoxic cardiomyocytes by regulating the EGLN1/HIF‑1α pathway

Wenmao Zhang Ziling Liao Chengfeng Xu Xinping Lin

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Abstract

Myocardial infarction is characterized by oxygen deficiency caused by arterial flow restriction. Salidroside (SAL) protects against myocardial damage via antioxidant production and inhibition of apoptosis. The present study aimed to investigate potential rescue mechanism of SAL on hypoxic cardiomyocytes. H9C2 cardiomyocytes were divided into normoxia, hypoxia and hypoxia + SAL groups. The inhibitory rate of hypoxia and the optimal concentration and rescue effect of SAL were determined using Cell Counting Kit-8 assay and flow cytometry. Ca

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Cite This Study

Zhang et al. (2024) studied this question.

synapsesocial.com/papers/68e55ef0e2b3180350efc48a https://doi.org/10.3892/br.2024.1868

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