Adeno-associated viruses (AAVs) are popular tools for gene delivery to animal models. Natural and engineered AAVs can even achieve widespread transduction of target organs through systemic delivery. Fast (<3 minute per mouse) and reproducible transduction through systemic AAV delivery can be achieved with retro-orbital injection. This protocol describes how to systemically deliver AAVs via the retro-orbital sinus.
No takes yet. Share an insight, caveat, or question.
Gerard Michael Coughlin (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: