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Takotsubo syndrome (TTS) is a reversible heart failure syndrome that frequently manifests with symptoms and electrocardiogram (ECG) changes that mimic those of an acute myocardial infarction (AMI). Historically, coronary artery disease (CAD) has been regarded as an exclusion criterion in the diagnosis of TTS. However, recent reports have challenged this viewpoint, suggesting that the two conditions may coexist. The present case series provides evidence that not only is TTS able to coexist with CAD, but that an acute coronary syndrome (ACS) can act as a trigger for the development of TTS.
Alirangues et al. (Sun,) studied this question.