Motivation The scToppR package provides a ToppGene interface from R programs/scripts to fully access/control the database for functional enrichment without the need for active interaction on its Web site (https://toppgene.cchmc.org/). Results The library facilitates the functional enrichment analysis and visualization by interacting with ToppGene, downloading the functional enrichment dataframes, and using R environment to visualize the final results. Availability Code and documentation are currently available at https://github.com/BioinformaticsMUSC/scToppR Supplementary information Supplementary data are available at Bioinformatics online.
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Granger et al. (2024) studied this question.
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