Evaluation of the antimicrobial activity of the alcoholic extract of Tagetes erecta against bacteria and fungi of clinical importance.

Antibiotic resistance is a significant global health concern, putting at risk treatment options for infectious diseases. As a result, treatments can be expensive and ineffective, so it is essential to look for new options such as the use of plant extracts with antimicrobial properties to combat these diseases. Tagetes sp is a plant species that is used in folk medicine to cure various diseases and has several properties among which the antimicrobial, for this reason, the aim of this research was to evaluate the antimicrobial activity of the ethanolic extract of Tagetes erecta L against various bacteria and yeasts. The antimicrobial activity of the extract was analyzed by the Kirby-Bauer method at different concentrations. The extract showed antimicrobial activity by presenting inhibition halos mainly against Staphylococcus, obtaining the following results: S. aureus ATCC 43300 (19,40 mm to 500 mg/mL); S. aureus ATCC 6538 (11,20 mm to 750 mg/mL); A. baumannii ATCC 19606 (10.57 mm a 250 mg/mL); P. mirabilis (7.63 mm a 250 mg/mL) e I. orientalis ATCC 6258 (7.40 mm a 250 mg/mL). Secondary metabolites such as tannins, quinones, coumarins, phenolic compounds and flavonoids were determined. Tagetes erecta L alcoholic extract has antimicrobial activity against clinically relevant strains and may be considered for further studies against multi-resistant microorganisms in the future.